Synthesis and antibacterial activity of 6- and 7- (2-(5-carboxyimidazole-4-carboxamido)phenylacetamido)-penicillins and cephalosporins.
- 1 January 1983
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 36 (3) , 242-249
- https://doi.org/10.7164/antibiotics.36.242
Abstract
The synthesis and antibacterial activity of a series of .beta.-lactam antibiotics having a 5-carboxyimidazole-4-carbonyl group attached through an amide linkage to ampicillin, cephaloglycin or their analogs are described. Some compounds of this series possessed high activity against Pseudomonas and other gram-negative bacteria.This publication has 2 references indexed in Scilit:
- The bacterial outer-membrane permeability of .BETA.-lactam antibiotics.The Journal of Antibiotics, 1979
- Semisynthetic .BETA.-lactam antibiotics. 8. Structure-activity relationships of .ALPHA.-sulfocephalosporins.The Journal of Antibiotics, 1976