Pro- and Anti-Inflammatory Cytokines in Primary Systemic Vasculitis
- 1 January 1993
- book chapter
- Published by Springer Nature
- Vol. 336, 341-344
- https://doi.org/10.1007/978-1-4757-9182-2_56
Abstract
The expression of cytokines that are potentially involved in the pathogenesis of vasculitis was studied in patients with primary systemic vasculitis (PSV). In extension of earlier reports, we detected an overexpression of transforming growth factor B (TGFB), interleukin 6 (IL6), and interleukin 8 (IL8), indicating that the whole cytokine cascade is activated to a significant extent in PSV.Keywords
This publication has 5 references indexed in Scilit:
- IL-8 as a circulating cytokine: induction by recombinant tumour necrosis factor-alphaClinical and Experimental Immunology, 1992
- Antineutrophil cytoplasmic autoantibodies: Immunobiological aspectsJournal of Molecular Medicine, 1991
- Pathologic concentrations of interleukin 6 inhibit T cell responses via induction of activation of TGF‐βThe FASEB Journal, 1991
- Intraperitoneal Injection of Human Recombinant Neutrophil‐Activating Factor/Interleukin 8 (hrNAF/IL‐8) Produces a T Cell and Eosinophil Infiltrate in the Guinea Pig Lung. Effect of PAF Antagonist WEB2086Annals of the New York Academy of Sciences, 1991
- Transforming growth factor beta and noncytopathic mechanisms of immunodeficiency in human immunodeficiency virus infection.Proceedings of the National Academy of Sciences, 1990