Further Studies on the Biosynthesis of 5-Hydroxytryptamine
- 1 September 1960
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 12 (1) , 617-623
- https://doi.org/10.1111/j.2042-7158.1960.tb12717.x
Abstract
The factors affecting the 5-hydroxytryptophan decarboxylase activity of the brain of animals have been studied. By altering the conditions of incubation and the amounts of the constituents of the incubation mixture, the activity as determined by the amount of 5-hydroxytryptamine formed has been increased about 10-fold. Intramuscular injections of cortisone and prednisolone did not reduce the enzyme activity although such treatment lowers the 5-hydroxytryptamine content of several tissues.Keywords
This publication has 1 reference indexed in Scilit:
- Studies on 5-Hydroxytryptamine and 5-HydroxytryptophanJournal of Pharmacy and Pharmacology, 1958