THE OXYGEN CONSUMPTION OF THE NORMAL AND THE DISEASED HUMAN KIDNEY 1

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Abstract
Renal oxygen consumption in unanesthetized human subjects was estimated by combining the techniques of intraven. catheterization and Na p-aminohippurate clearance. The mean normal renal oxygen extraction was found to be 1.42 volumes % and the mean normal renal oxygen consumption 16 cc./min. Decreased levels of oxygen consumption were found in patients with nephrosclerosis, chronic glomerulonephritis, and chronic pyelonephritis, who also had diminished renal blood flow. Oxygenex-traction was normal in these patients. In patients with acute and subacute glomerulonephritis the extraction of oxygen was decreased in spite of a normal or increased renal blood flow.