Effect of Angiotensin on Plasma‐Free Fatty Acids in Dogs

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Abstract
Mechanisms underlying the plasma‐free fatty acids (FFA) lowering effect of angiotensin have been studied in anesthetized dogs. Angiotensin in pressor doses reduced fatty tissue blood flow (FBF) as well as plasma‐FFA. After ganglionic blockade, angiotensin had the opposite effects, as a slight increase was found in FBF and plasma‐FFA. Atropine or a β‐adrenergic blocking agent did not interfere with the angiotensin effect on plasma‐FFA. It is concluded that the angiotensin action on plasma FFA is secondary to its vasoconstrictive effect in adipose tissue.