Copper Distribution in Milk during Early Lactation

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Abstract
Cu64 was used to determine the distribution of natural copper in milk at intervals during early lactation. The amount of copper associated with fat globules was about 15% after 2 and 4 weeks of lactation and 35% after 10 weeks. The change in copper distribution was accompanied by a change in susceptibility to oxidized flavor. A combination of cream washing and chelation by EDTA removed up to 90% of lipid bound copper. When such treated fat globules were added back to and recovered from the original skimmilk, their copper content increased. Administration of Cu64 by infusion or by drench yielded similar results with respect to distribution, but rate of appearance in milk was slower by drenching.

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