USE OF BIOTINYLATED DNA PROBES IN SCREENING CELLS OBTAINED FROM CERVICAL SWABS FOR HUMAN PAPILLOMAVIRUS DNA-SEQUENCES
- 1 November 1986
- journal article
- research article
- Vol. 30 (6) , 603-607
Abstract
A nonradioactive DNA-detection procedure using biotinylated DNA probes in the screening of cells from cervical swabs for DNA sequences homologous to human papillomavirus (HPV) DNA was tested. This alternative DNA-detection method yielded results comparable to those obtained with radioisotope-labeled DNA probes in 32 cases tested. This procedures obviates the special precautions required for radioisotope materials. Accordingly, this technique can be made available to many laboratories, and conclusive evidence as to the relation of HPV infection to cervical cancer may thus be accumulated.This publication has 10 references indexed in Scilit:
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