THE TREATMENT OF RHEUMATOID ARTHRITIS WITH LARGE DOSES OF VITAMIN D

29 October 1938

journal article
research article
Published by American Medical Association (AMA) in JAMA

Vol. 111 (18) , 1632-1639
https://doi.org/10.1001/jama.1938.02790440026006

Abstract

In 1935 Dreyer and Reed¹reported that they had previously observed²marked clinical improvement in the rheumatoid arthritis of two patients during the time they were receiving massive doses of vitamin D for hay fever. This original report and other reports by the same authors³have resulted in an increasing interest in the value of vitamin D in the treatment of rheumatoid arthritis as shown by subsequent reports.⁴ Knowing that generalized decalcification is a common and at times an early manifestation of rheumatoid arthritis, one might be led to suspect that the chance observation of Dreyer and his co-workers⁵indicated that certain patients with rheumatoid arthritis suffer from some type of disease of calcium and phosphorus deficiency. If such were the case, then this chance observation might be of etiologic as well as of therapeutic significance. However, detailed studies of the calcium and phosphorus metabolism

Keywords

This publication has 1 reference indexed in Scilit:

TREATMENT OF ATROPHIC ARTHRITIS
JAMA, 1936