Sister chromatid exchange in dyskeratosis congenita lymphocytes.
Open Access
- 1 August 1977
- journal article
- research article
- Published by BMJ in Journal of Medical Genetics
- Vol. 14 (4) , 256-257
- https://doi.org/10.1136/jmg.14.4.256
Abstract
Sister chromatid exchange (SCE) frequency in chromosomes from lymphocytes of a patient with dyskeratosis congenita was 12-2 per mitosis. Our 33 normal controls had a mean of 5-4 SCE per mitosis and 5 patients with Fanconi's anaemia averaged 7-6 SCE per mitosis. The rate of chromosome breakage was only 0-5% in the dyskeratosis congenita patient and 0 to 2-5% in controls, while the Fanconi's anaemia patients showed higher values.This publication has 12 references indexed in Scilit:
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