Evidence against VIP-involvement in neurogenic relaxations of the mouse anococcygeus muscle

1 October 1986

journal article
research article
Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology

Vol. 38 (10) , 767-769
https://doi.org/10.1111/j.2042-7158.1986.tb04488.x

Abstract

Vasoactive intestinal polypeptide (VIP) antiserum, α-chymotrypsin, and repeated exposure to VIP markedly reduced relaxations of the mouse anococcygeus muscle to VIP but not to field stimulation. This evidence suggests that VIP does not mediate non-adrenergic, non-cholinergic relaxations in the mouse anococcvpeus.

This publication has 8 references indexed in Scilit:

Interaction of Growth Hormone-Releasing Factor (GRF) and 14 GRF Analogs with Vasoactive Intestinal Peptide (VIP) Receptors of Rat Pancreas. Discovery of (N-Ac-Tyr¹,D-Phe²)-GRF(l-29)-NH₂as a VIP Antagonist*
Endocrinology, 1985
Evidence for vasoactive intestinal polypeptide as a neurotransmitter in smooth muscle of the urogenital tract
Brain Research, 1984
Vasoactive intestinal polypeptide: a putative transmitter in the canine gastric muscularis mucosa.
The Journal of Physiology, 1983
Vasoactive Intestinal Peptide: A Possible Transmitter of Nonadrenergic Relaxation of Guinea Pig Airways
Science, 1980
A smooth muscle inhibitory material from the bovine retractor penis and rat anococcygeus muscles.
The Journal of Physiology, 1980
EVIDENCE FOR PURINERGIC INNERVATION OF THE ANOCOCCYGEUS MUSCLE
British Journal of Pharmacology, 1978