HIGH INCIDENCE OF NORMAL THYROID GLAND VOLUME IN PATIENTS WITH GRAVES' DISEASE

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Abstract
Thyroid function and thryoid gland volume, ultrasonically determined, were investigated in 90 consecutive untreated patients with Graves'' disease. Twenty-eight patients (31%) had no clinically detectable goiter. Median thyroid gland volume was 31 ml (range 12-99 ml). Twenty-one patients (23%) had a normal calculated thyroid volume. Thyroid volume did not correlate with any measure of thyroid function. The lack of a goiter in a large portion of patients with Graves'' disease could be responsible for delayed diagnosis and subsequent treatment of these patients.