Clinical Outcomes by Race in Hypertensive Patients With and Without the Metabolic SyndromeAntihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)
Open Access
- 28 January 2008
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of internal medicine (1960)
- Vol. 168 (2) , 207-217
- https://doi.org/10.1001/archinternmed.2007.66
Abstract
Hypertensive patients with the metabolic/cardiometabolic syndrome (MetS) are at especially high risk for complications of cardiovascular disease (CVD).1-3 In addition, racial differences in the presentation of MetS are well documented. For example, when compared with white patients, black patients with MetS have a higher prevalence of elevated blood pressure, type 2 diabetes mellitus, and obesity but lower levels of triglycerides and higher levels of high-density lipoprotein cholesterol.1 The primary management strategy for MetS includes lifestyle changes, optimization of blood pressure (BP) control, and reduction of other cardiovascular risk factors.1,2This publication has 32 references indexed in Scilit:
- Effects of Different Blood Pressure–Lowering Regimens on Major Cardiovascular Events in Individuals With and Without Diabetes MellitusArchives of internal medicine (1960), 2005
- Clinical Outcomes in Antihypertensive Treatment of Type 2 Diabetes, Impaired Fasting Glucose Concentration, and NormoglycemiaArchives of internal medicine (1960), 2005
- Renal Outcomes in High-Risk Hypertensive Patients Treated With an Angiotensin-Converting Enzyme Inhibitor or a Calcium Channel Blocker vs a DiureticArchives of internal medicine (1960), 2005
- Outcomes in Hypertensive Black and Nonblack Patients Treated With Chlorthalidone, Amlodipine, and LisinoprilJAMA, 2005
- The association of hypertension and diabetes: prevalence, cardiovascular risk and protection by blood pressure reductionActa Diabetologica, 2005
- Long-term effect of diuretic-based therapy on fatal outcomes in subjects with isolated systolic hypertension with and without diabetesThe American Journal of Cardiology, 2005
- Diagnostic and Therapeutic Implications of Relationships Between Fasting, 2-Hour Postchallenge Plasma Glucose and Hemoglobin A1c ValuesArchives of internal medicine (1960), 2004
- Hypertension, the Metabolic Syndrome, and the Risk of Developing Diabetes: Is It Time to Change the Guidelines?The Journal of Clinical Hypertension, 2004
- Rationale and Design for the Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)American Journal of Hypertension, 1996
- Increased risk of non-insulin-dependent diabetes mellitus in elderly hypertensive subjectsJournal Of Hypertension, 1994