A NEW APPROACH IN RECOGNITION OF HETEROCHROMATIC REGIONS OF HUMAN-CHROMOSOMES BY MEANS OF RESTRICTION ENDONUCLEASES
- 1 January 1988
- journal article
- research article
- Vol. 42 (1) , 60-65
Abstract
The heteromorphisms of C-band regions of human chromosomes are evaluated by means of restriction endonucleases AluI, DdeI, MboI, and RsaI. Every chromosome exhibits heteromorphic markers of the C-band regions except chromosome 8. Each enzyme was found to be highly characteristic in its staining profile, a result that clearly suggests the diversity of heterochromatin. The inherent C-band-region heterochromatin variability that is revealed by these enzymes provides a valuable tool in identifying markers as compared with other previously described techniques.This publication has 14 references indexed in Scilit:
- AluI-resistant chromatin of chromosome 18: classification, frequencies and implicationsChromosoma, 1987
- Mechanism of endonuclease banding of chromosomesExperimental Cell Research, 1984
- The action of ultraviolet light on the patterns of banding induced by restriction endonucleases in human chromosomesChromosoma, 1984
- Restriction enzyme banding of mouse metaphase chromosomesChromosoma, 1984
- Chromosome Localization of Highly Repetitive Human DNA's and Amplified Ribosomal DNA with Restriction EnzymesScience, 1983
- Chromatin organization and restriction endonuclease activity on human metaphase chromosomesCytogenetic and Genome Research, 1983
- New C band markers of human chromosomes: C band position variants.Journal of Medical Genetics, 1980
- Human Chromosomal Heteromorphisms: Nature and Clinical SignificancePublished by Elsevier ,1980
- Localization of transcripts produced in vivo and in vitro on phage SP82 genomeGene, 1977