The preferred rotamer about the C5—C6 bond of D-galactopyranoses and the stereochemistry of dehydrogenation by D-galactose oxidase
- 1 June 1987
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 65 (6) , 1145-1153
- https://doi.org/10.1139/v87-191
Abstract
1H nuclear magnetic resonance studies on D-galactopyranoses with chirally deuterated hydroxymethyl groups revealed that the preferred rotamer about the C5—C6 bond of the D-galactopyranoses was not tg but gt. Studies on the stereochemistry of dehydrogenation of D-galactose oxidase from Dactyliumdendroides with chirally pure deuterated methyl β-D-galactopyranosides showed that there were two mechanisms for the enzymatic reaction: an efficient pro-S hydrogen atom specific oxidation and a far less efficient non-specific or pro-R specific oxidation.This publication has 4 references indexed in Scilit:
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