Microbiosensors using electrodes made in Si-technology
- 1 January 1997
- book chapter
- Published by Springer Nature
- Vol. 80, 267-283
- https://doi.org/10.1007/978-3-0348-9043-4_17
Abstract
The combination of electrochemical transducers made in silion technology with chemical and biochemical components has been used to manufacture miniaturized sensor structures. Three different types of sensors have been developed and optimized for practical use: (i) an ion-selective sensor, (ii) a glucose enzyme sensor, (iii) a redox-amplifying sensor for immunosensing. The immunodetection based on the redox recycling of mediator molecules is shown for low and high molecular weight analytes. The sensors have been integrated with miniaturized fluidic components and combined with sensor-related electronics and a common microcontroller.Keywords
This publication has 27 references indexed in Scilit:
- Chemical microsensor systems for medical applications in cathetersSensors and Actuators B: Chemical, 1995
- Highly sensitive electrochemical microsensensors using submicrometer electrode arraysSensors and Actuators B: Chemical, 1995
- Properties of interdigital electrode arrays with different geometriesAnalytica Chimica Acta, 1995
- Development of Durable K+-Selective Chemically Modified Field Effect Transistors with Functionalized Polysiloxane MembranesAnalytical Chemistry, 1994
- Micromachined ion-selective electrodes with polymer matrix membranesSensors and Actuators B: Chemical, 1994
- Miniature electrochemical glucose biosensorsAnalytica Chimica Acta, 1993
- Small-volume voltammetric detection of 4-aminophenol with interdigitated array electrodes and its application to electrochemical enzyme immunoassayAnalytical Chemistry, 1993
- Microfabrication Techniques for Integrated Sensors and MicrosystemsScience, 1991
- Polyurethane Enzyme Membranes for Chip BiosensorsAnalytical Letters, 1989
- p-aminophenyl phosphate: an improved substrate for electrochemical enzyme immnoassayAnalytica Chimica Acta, 1988