BIOCHEMICAL CHARACTERIZATION OF SYRIAN HAMSTER CELL SURFACE ALLOANTIGENS. III. HAMSTER ALLOANTISERA IMMUNOPRECIPITATE CLASS II-LIKE, BUT NOT CLASS I-LIKE, MOLECULES

Publisher Website
Google Scholar
Abstract
Twelve hamster alloantisera, recently produced by mutual immunizations of domestic inbred strains and recently wild, partially inbred lines, identify 2 cell surface molecules, 29 and 39 kilodaltons, expressed by hamster lymphohematopoietic cells. Their expression on lymph node and spleen cells suggests that hamster T cells display cell surface class II homologs. None of the alloantisera identify putative hamster homologues of class I MHC [major histocompatibility complex] molecules. Apparently hamsters possess a chromosomal region, tentatively designated Hm-1, that comprises genetic loci encoding alloantigens detectable by mixed lymphocyte reactivity and by serology, a region that resembles the I region of murine H-2.