The influence of a low and high calcium diet on the development and chemical composition of the skeleton in swine

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Abstract
(1) The skeletons of young pigs on a ration composed mainly of cereal grains but with the addition of cod-liver oil show a very distinct lack of calcification, the percentage of ash being about 12 per cent. lower than in the bones of normal animals. (2) Calcification of the bones proceeds up to maturity. A difference of about 360 gm. tricalcic phosphate was found between the same mature bones of normal and calcium-deficient animals. (3) The ratio of lime to phosphate is almost the same in the different bones of the same individual as well as in the normal and rachitic bones of swine. The main characteristic of the bones in low-calcium rickets is a low-ash content, but the composition of the ash is normal.