Health-Related Quality of Life Outcomes Following Elective Open or Endovascular AAA Repair:A Randomized Controlled Trial

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Abstract
To assess health-related quality of life outcomes after endovascular versus open abdominal aortic aneurysm repair. Participants were randomly assigned to receive either endovascular or open abdominal aortic aneurysm (AAA) surgery according to a rate of 3 endovascular patients to 1 with open repair. Data on patient characteristics, operative aspects, and procedural and device-related complications were compiled at a single center. Health-related quality of life was assessed before treatment and 1 and 3 months following operation using the Medical Outcomes Study Short-Form 36-item Health Survey (SF-36) and the EuroQol questionnaire. Between 1996 and 1999, 57 patients (54 men; mean age 69 years, range 52-82) underwent endovascular and 19 patients (16 men; mean age 68 years, range 52-81) underwent open AAA repairs. Preoperatively, comparable scores were recorded in both treatment groups. One month after operation, patients of both groups scored significantly lower on the SF-36 domains of Role Limitations due to physical problems and Pain compared to preoperative scores. Three months after operation, both groups had scores in all domains comparable to preoperative levels of functioning. There was a significant benefit for the endovascular group 1 month after operation in the SF-36 domains of Physical Functioning, Role Limitations due to physical problems, Vitality, and Pain; their score on the EuroQol Usual Activities item was also significantly better. After 3 months, there were no longer differences between groups. Short-term health-related quality of life benefits were found after endovascular repair compared with standard open surgery.

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