Studies in myasthenia gravis. Heat stability and species specificity of active muscle antigens.
- 1 June 1973
- journal article
- Vol. 24 (6) , 1035-40
Abstract
Both myosin and actomyosin, active antigens related to antibody induction in myasthenia gravis, show different stabilities. With time or increasing heat treatment, myosin rapidly loses antigenic activity. While actomyosin showed lower initial antigenic activity, both with time and various heat treatments it showed greater stability and final activity. Utilization of actomyosin from several animal sources showed antigenic sites were species related. Human, monkey and rabbit actomyosin were good sources of antigen for studies with human myasthenic sera.This publication has 12 references indexed in Scilit:
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