The Design of a Simple Microflowmeter for Biological Perfusion Experiments

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Abstract
Various types of flowmeters are discussed with reference to their use at very small flows. The differential pressure type, using rubber membranes, appears most suitable. The steps are outlined in the design of an instrument sensitive to flows as low as 0.01 ml/min. yet with a response time less than 10 sec. In this instrument a completely differential linkage between two membranes is accomplished by the use of an incompressible fluid. The theory of the response is developed. This gives a prediction of the speed of response from the sensitivity and the diameter of the membrane used.

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