β‐Subunit of baboon chorionic gonadotropin Continuous flow Fmoc‐polyamide synthesis of the C‐terminal 37‐peptide
- 12 January 1988
- journal article
- research article
- Published by Wiley in International Journal of Peptide and Protein Research
- Vol. 31 (1) , 47-57
- https://doi.org/10.1111/j.1399-3011.1988.tb00005.x
Abstract
The synthesis of a 37-peptide fragment derived from the carboxyl terminal of the β-subunit of baboon chorionic gonadotropin has been accomplished by the continuous flow Fmoc-polyamide solid phase method. The use of N′-fluorenylmethoxy-carbonyl-glutamine with its sidechain protected by the 4.4′-dimethoxybenzhydryl group enabled successful incorporation of this residue onto a hydroxymethyl linkage agent without apparent side reaction.Keywords
This publication has 38 references indexed in Scilit:
- Studies on peptides. CXXVII. Synthesis of a tripentacontapeptide with epidermal growth factor activity.CHEMICAL & PHARMACEUTICAL BULLETIN, 1985
- Further studies on the use of multi-substituted benzenesulfonyl groups for protection of the guanidino function of arginine.CHEMICAL & PHARMACEUTICAL BULLETIN, 1981
- Localization of the β subunit of human chorionic gonadotrophin on various tumorsPublished by Elsevier ,1980
- Structure of human luteinizing hormone beta subunit: Evidence for a related carboxyl-terminal sequence among certain peptide hormonesBiochemical and Biophysical Research Communications, 1979
- New method for removing the S-p-methoxybenzyl and S-t-butyl groups of cysteine residues with mercuric trifluoroacetate.CHEMICAL & PHARMACEUTICAL BULLETIN, 1978
- Synthesis, purification, and chemical characterization of the amino-terminal 1-34 fragment of bovine parathyroid hormone synthesized by the solid-phase procedureBiochemistry, 1977
- Regulation of the primate fetal adrenal gland and testis in vitro and in vivoJournal of Steroid Biochemistry, 1977
- Synthesis of N-alkylimidazoles from N-alkyloxazolium salts.CHEMICAL & PHARMACEUTICAL BULLETIN, 1976
- Anomalous cleavage of aspartyl-proline peptide bonds during amino acid sequence determinationsBiochemical and Biophysical Research Communications, 1970
- UNEXPECTED FORMATION OF ANHYDRO COMPOUNDS IN THE SYNTHESIS OF ASPARAGINYL AND GUTAMINYL PEPTIDES1Journal of the American Chemical Society, 1956