Interrelationship between affinity for DNA, cytotoxicity and induction of DNA-breaks in cultured L1210 cells for two series of tricyclic intercalators: Simplified analogues of ellipticine derivatives
- 1 May 1989
- journal article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 38 (9) , 1395-1406
- https://doi.org/10.1016/0006-2952(89)90178-0
Abstract
No abstract availableKeywords
This publication has 25 references indexed in Scilit:
- 1-Amino-substituted 4-methyl-5H-pyrido[4,3-b]indoles (.gamma.-carbolines) as tricyclic analogs of ellipticines: a new class of antineoplastic agentsJournal of Medicinal Chemistry, 1988
- 1-Amino-substituted 4-methyl-5H-pyrido[3',4':4,5]pyrrolo[3,2-c]pyridines: a new class of antineoplastic agentsJournal of Medicinal Chemistry, 1987
- Synthèse d'analogues tricycliques des ellipticines : les methyl-4,5h-pyrido [4,3-b] indoles (γ-carbolines) diversement substttus sur leurs sommets 1,5 et 8.Tetrahedron, 1987
- Premiere synthese de methyl-4-5h- pyrido ¦3',4':4,5¦pyrrolo ¦3,2-c¦pyridines, analogues tricycliques des aza-9 ellipticinesTetrahedron, 1986
- Autre voie d'acces aux 5h-pyrido ¦3',4':4,5¦pyrrolo ¦3,2-c¦pyridines et leur transformation en derives n-5 et n-8 substituesTetrahedron, 1986
- Adriamycin-Induced DNA Damage Mediated by Mammalian DNA Topoisomerase IIScience, 1984
- Formation and rejoining of deoxyribonucleic acid double-strand breaks induced in isolated cell nuclei by antineoplastic intercalating agentsBiochemistry, 1984
- Protein-associated deoxyribonucleic acid strand breaks produced in mouse leukemia L1210 cells by ellipticine and 2-methyl-9-hydroxyellipticiniumBiochemical Pharmacology, 1982
- Protein-associated deoxyribonucleic acid strand breaks in L1210 cells treated with the deoxyribonucleic acid intercalating agents 4'-(9-acridinylamino)methanesulfon-m-anisidide and adriamycinBiochemistry, 1981
- Ellipticine and derivatives induce breakage of L1210 cells DNA in vitroBiochemical Pharmacology, 1979