The synthesis of stereoselectively labelled porphobilinogen and its incorporation into protoporphyrin-IX
- 1 August 1987
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 43 (8) , 892-894
- https://doi.org/10.1007/bf01951654
Abstract
11-(R)-2H porphobilinogen, stereospecifically labelled with deuterium in the aminomethylene group has been incorporated into protoporphyrin-IX by haemolysates of chicken erythrocytes. High field NMR spectroscopy confirms that the overall biochemical process is stereospecific, deuterium being retained at the α-, γ-and δ-meso positions and lost from the β-meso position.This publication has 7 references indexed in Scilit:
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