GLOMERULAR LESIONS IN ARGYRIC NZB-NZW MICE

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  • 1 January 1977
    • journal article
    • research article
    • Vol. 58  (1) , 57-62
Abstract
Glomerular basement membranes showed strong Ag labeling on EM in NZB/NZW mice fed 12 mmol AgNO3 for 6 wk at ages from 1-7 mo. Although some Ag granules were seen within mesangial immune deposits following their concurrent deposition, Ag was usually deposited in electron-lucent areas around pre-existing deposits, or it formed a boundary to an expanded mesangium when immune deposits subsequently developed. Immune deposits in capillary loops occurred on the outer or inner aspect of the zone of Ag labeling.