Prevention of Surgical Oliguria and Renal-Hemodynamic Suppression by Sustained Hydration

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Abstract
ANESTHESIA and surgery in man is frequently associated with acute depression of renal function and is occasionally followed by oliguric renal failure.1 2 3 4 Previous attempts have been made to minimize these effects by water and electrolyte infusions varying in quantity, electrolyte composition and time given in relation to the operative procedure. No acceptable method was found.5 , 6 The precipitation of cardiocirculatory overload and water intoxication in some patients offered a rationale for the fluid restriction applied by most physicians.5 , 7 Oliguria has usually been accepted as an inevitable, if undesirable, accompaniment of anesthesia and surgery.We have undertaken studies to re-examine the relations . . .