Prevention of Clostridium difficile induced mortality in gnotobiotic mice by Saccharomyces boulardii
- 1 November 1986
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Microbiology
- Vol. 32 (11) , 894-896
- https://doi.org/10.1139/m86-164
Abstract
Oral preventive treatment of gnotobiotic mice by Saccharomyces boulardii significantly decreased mortality following Clostridium difficile infection. A single S. boulardii ingestion protected 16% of mice, whereas 56% were protected when S. boulardii was given continuously in the drinking water. No direct antagonistic effect of the yeast on C. difficile numbers was detected, whereas a modulation of fecal cytotoxin production was demonstrated.This publication has 7 references indexed in Scilit:
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