Sarcoidosis and Primary Biliary Cirrhosis

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Abstract
Sarcoidosis is a systemic granulomatous disorder of unknown cause that involves many organs. The most characteristic clinical presentations of sarcoidosis include pulmonary infiltrates, lymphadenopathy, fever, infiltrative skin lesions, and uveitis. In the absence of a known cause, the diagnosis of sarcoidosis is made from demonstration of granulomatous inflammation in more than one organ in a patient in whom other causes of granulomatous disease have been excluded. The Kveim-Siltzbach skin test is positive in approximately 80 per cent of patients but is not universally available or well standardized.1 Granulomas in the liver are found in most patients with sarcoidosis, and liver . . .

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