Evaluation of starch obtained from Ensete ventricosum as a binder and disintegrant for compressed tablets
- 1 April 1993
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 45 (4) , 317-320
- https://doi.org/10.1111/j.2042-7158.1993.tb05560.x
Abstract
The binding and disintegrant properties of starch obtained from Ensete ventricosum Musaceae have been evaluated. The effect of the starch on the physical properties such as crushing strength, friability and disintegration time of tablets of chloroquine phosphate, dipyrone and paracetamol was compared with tablets prepared with potato starch. The results show that enset starch can be used both as a tablet binder and disintegrant and the indication is that enset starch has a better binding ability and less disintegrating power than potato starch.Keywords
This publication has 8 references indexed in Scilit:
- Multiple Compression and Plasto-elastic Behaviour of Paracetamol and Microcrystalline Cellulose MixturesJournal of Pharmacy and Pharmacology, 1988
- The prediction of paracetamol capping tendenciesJournal of Pharmacy and Pharmacology, 1982
- The influence of binder concentration on the bond formation of pharmaceutical granulesJournal of Pharmacy and Pharmacology, 1979
- Factors affecting the disintegration and dissolution of chloroquine phosphate/starch tabletsJournal of Pharmacy and Pharmacology, 1978
- The effect of some binding agents on the mechanical properties of granules and their compression characteristicsJournal of Pharmacy and Pharmacology, 1977
- The effect of waxes, hydrolysed gelatin and moisture on the compression characteristics of paracetamol and phenacetinJournal of Pharmacy and Pharmacology, 1976
- Some formulation factors affecting the tensile strength, disintegration and dissolution of uncoated oxytetracycline tabletsJournal of Pharmacy and Pharmacology, 1976
- Utilization of Hydrophilic Gums for the Control of Drug Release from Tablet Formulations I. Disintegration and Dissolution BehaviorJournal of Pharmaceutical Sciences, 1966