The effect of coumarin derivatives on the immunological system of man
- 1 January 1983
- journal article
- research article
- Published by Springer Nature in Inflammation Research
- Vol. 13 (1) , 50-52
- https://doi.org/10.1007/bf01994281
Abstract
Peripheral blood lympocyte mitogen responsiveness was studied in 12 normal and 51 cancer patients. One group of patients was treated with warfarin, the second group with coumarin. There was a significant increase in lymphocyte response to phytohaemagglutinin (PHA) following both drugs. This increase indicates that both agents are capable of activating lymphocytes and thus stimulating some immunological functions.This publication has 14 references indexed in Scilit:
- Influence of anti-inflammatory drugs on the interaction of lymphocytes and macrophagesInflammation Research, 1980
- A comparison of coumarin and levamisole on parameters of the inflammatory responseInflammation Research, 1979
- MORPHOLOGICAL ASSESSMENT OF STIMULATORY EFFECT OF COUMARIN ON MACROPHAGES1978
- Mechanisms of Extracellular Killing of Nucleated Mammalian Cells by MacrophagesPublished by Elsevier ,1976
- Macrophage content of tumours in relation to metastatic spread and host immune reactionNature, 1974
- CLOTTING FACTORS AND METASTASIS FORMATIONAmerican Journal of Roentgenology, 1971
- Warfarin Treatment of Mice Bearing Autochthonous Tumors: Effect on Spontaneous MetastasesScience, 1968
- Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.1968
- Anticoagulants and the Development of Pulmonary MetastasesArchives of Surgery, 1962
- TRANSFORMATION OF THE SMALL LYMPHOCYTE IN CULTUREThe Lancet, 1961