MspI polymorphic site within the Factor IX gene
- 1 July 1987
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 76 (3) , 262-264
- https://doi.org/10.1007/bf00283620
Abstract
We have localized the position of the MspI polymorphic site that exists within the factor IX gene. The location of the MspI polymorphic site is within intro D, 1.9 kb upstream from the beginning of exon V and 4 kb downstream from a known polymorphic TaqI site. The use of a specific genomic probe simplifies the interpretation of the MspI polymorphism by reducing the number of non-overlaping DNA fragments to three bands; 2.4, 3.4, and 5.8 kb.Keywords
This publication has 14 references indexed in Scilit:
- Detection of specific sequences among DNA fragments separated by gel electrophoresisPublished by Elsevier ,2006
- DIAGNOSIS OF HAEMOPHILIA B CARRIERS USING INTRAGENIC OLIGONUCLEOTIDE PROBESThe Lancet, 1986
- USE OF A BAMHI POLYMORPHISM IN THE FACTOR-IX GENE FOR THE DETERMINATION OF HEMOPHILIA-B CARRIER STATUS1986
- A new MspI restriction fragment length polymorphism in the hemophilia B locusHuman Genetics, 1985
- Complete nucleotide sequences of the gene for human factor IX (antihemophilic factor B)Biochemistry, 1985
- Carrier detection in haemophilia B using two further intragenic restriction fragment length polymorphismsNucleic Acids Research, 1984
- CHARACTERISATION AND USE OF AN INTRAGENIC POLYMORPHIC MARKER FOR DETECTION OF CARRIERS OF HAEMOPHILIA B (FACTOR IX DEFICIENCY)The Lancet, 1984
- Regional localization on the human X chromosome and polymorphism of the coagulation factor IX gene (hemophilia B locus).Proceedings of the National Academy of Sciences, 1984
- Molecular genetics of human serum albumin: restriction enzyme fragment length polymorphisms and analbuminemia.Proceedings of the National Academy of Sciences, 1983
- Isolation and characterization of a cDNA coding for human factor IX.Proceedings of the National Academy of Sciences, 1982