GENTAMICIN IN THE TREATMENT OF PURULENT MENINGITIS IN NEONATES AND INFANTS

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Abstract
Summary: Twenty‐one infants with purulent meningitis, who failed to improve after a 5–6 days parenteral administration of ampicillin, alone or in combination with kanamycin in appropriate doses, were subsequently treated with gentamicin. Two infants died and one developed hydro‐cephaly, but the remaining 18 recovered and the cure seems complete and permanent. Although gentamicin is an ototoxic drug, it might be used for therapy, in some cases of purulent meningitis in infancy when the other less toxic antimicrobial agents are not effective.

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