Bis-des-hydroxy, bis-des-methoxy cc-1065. Synthesis, DNA binding, andbiological activity.

This publication has 11 references indexed in Scilit:

• Studies on the total synthesis of CC-1065: preparation of a synthetic simplified 3-carbamoyl-1,2-dihydro-3H-pyrrolo[3,2-e]indole dimer/trimer/tetramer (CDPI dimer/trimer/tetramer) and development of methodology for PDE-I dimer methyl ester formation
  The Journal of Organic Chemistry, 1987
• Total synthesis of U- 71,184, s potent new antitumor agent modeled on cc-1065
  Tetrahedron Letters, 1986
• Construction and characterization of a site-directed CC-1065-N3-adenine adduct within a 117 base pair DNA restriction fragment
  Biochemistry, 1986
• Covalent binding of antitumor antibiotics in the minor groove of DNA. Mechanism of action of CC-1065 and the pyrrolo(1,4)benzodiazepines
  Accounts of Chemical Research, 1986
• The chemistry, mechanism of action and biological properties of CC-1065, a potent antitumor antibiotic.
  The Journal of Antibiotics, 1986
• Reaction of the antitumor antibiotic CC-1065 with DNA. Location of the site of thermally induced strand breakage and analysis of DNA sequence specificity
  Biochemistry, 1985
• Binding of CC‐1065 to poly‐ and oligonucleotides
  Biopolymers, 1985
• The molecular origin of DNA-drug specificity in netropsin and distamycin.
  Proceedings of the National Academy of Sciences, 1985
• Reaction of the Antitumor Antibiotic CC-1065 with DNA: Structure of a DNA Adduct with DNA Sequence Specificity
  Science, 1984
• Characterization of an adduct between CC-1065 and a defined oligodeoxynucleotide duplex
  Nucleic Acids Research, 1984