Is there a predisposition for meiotic non‐disjunciton that may be detected by mitoitc hyperploidy?
- 1 September 1983
- journal article
- Published by Wiley in Clinical Genetics
- Vol. 24 (3) , 184-190
- https://doi.org/10.1111/j.1399-0004.1983.tb02237.x
Abstract
The aneuploidy frequencies have been stuided in vitro in lymphocytes from couples with recurent abortions, from parents of a trisomic child and from control couples with at least two normal children; c‐heterochromatin variants have been analysed on the same samples by length measurements.A significant increase of hyeperploid cells has been observed in the lymphocytes from parents of a trisomic and couples with recurrent abortions as well. However, no consistent correlation has been found so far between c‐heterochromatin varients and an increase of aneuploidy.Keywords
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