THE CALORIGENIC EFFECTS OF SOME THYROXINE ANALOGS ON INTACT ANIMALS AND ON EXCISED TISSUES*
Open Access
- 1 April 1962
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 41 (4) , 696-701
- https://doi.org/10.1172/jci104527
Abstract
The L- and D-isomers of thyroxine and triiodothyronine and their propionic and acetic acid derivatives were studied in thyroidectomized rats. Within moderate dose range, the oxygen consumption of excised liver, kidney, heart, and diaphragm paralleled the change in whole animal''s BMR, although the response of heart was consistently higher than that of the other tissues. Therefore a rise of the heart metabolism may not be reflected by a measurable increase of BMR.Keywords
This publication has 17 references indexed in Scilit:
- Effect of D-Thyroxine on Serum CholesterolBMJ, 1961
- Heart rate and O2 consumption after triiodothyronine in the myxedematous rabbitAmerican Journal of Physiology-Legacy Content, 1961
- ANTIMETABOLIC ACTIVITY OF 3, 3', 5'-TRIIODO-DL-THYRONINE IN MAN1960
- Antithyroxine effects of some thyroxine analoguesAmerican Journal of Physiology-Legacy Content, 1959
- Physiological disposition of d- and l-thyroxine in the ratAmerican Journal of Physiology-Legacy Content, 1959
- ANTIGOITROGENIC AND CALORIGENIC ACTIVITIES OF THYROXINE ANALOGUES IN RATS1Endocrinology, 1959
- METABOLIC ACTIONS OF THYROXINE DERIVATIVES AND ANALOGS1Endocrinology, 1956
- EFFECT OF TRIIODOTHYROACETIC ACID ON BLOOD-CHOLESTEROL LEVELSThe Lancet, 1956
- Metabolism of Tissues Excised From Thyroxine-Injected RatsAmerican Journal of Physiology-Legacy Content, 1952
- A Limited Feeding Regime for Rats.Experimental Biology and Medicine, 1949