The lactam‐amino acid equilibria for ethylpyrrolidone and polyvinylpyrrolidone
- 1 January 1954
- journal article
- research article
- Published by Wiley in Journal of Polymer Science
- Vol. 12 (1) , 565-575
- https://doi.org/10.1002/pol.1954.120120149
Abstract
The lactam‐amino acid equilibria of N‐ethylpyrrolidone and poly‐N‐vinylpyrrolidone were studied in dilute aqueous solutions and in n‐butanol at 100°C. and compared with earlier investigations of similar systems. It was found that with in the intermediate pH range the lactam is the predominant form. Below and above certain critical acid and alkaline pH values increasing amounts of amino acid will be formed. It has been shown that these critical pH values are closely related to pK1 and pK2 of the corresponding amino acid. The polymeric lactam PVP is more resistant against hydrolysis than the low molecular lactams. This effect is due to the polyampholyte character of the polymeric amino acid formed in the course of the hydrolysis reaction.Keywords
This publication has 6 references indexed in Scilit:
- AN INTERPRETATION OF THE KINETICS OF GLUTAMIC ACID LACTAM FORMATIONJournal of Biological Chemistry, 1950
- THERMODYNAMIC PROPERTIES OF SOLUTIONS OF AMINO ACIDS AND RELATED SUBSTANCESPublished by Elsevier ,1937
- THE GLUTAMIC ACID-PYRROLIDONECARBOXYLIC ACID SYSTEMPublished by Elsevier ,1937
- The Temperature Variation of Ionization Constants in Aqueous SolutionsJournal of the American Chemical Society, 1934
- Synthesis of a Series of Alpha-Substituted N-MethylpyrrolinesJournal of the American Chemical Society, 1933
- Reduction von Succinimiden zu PyrrolidonenEuropean Journal of Inorganic Chemistry, 1900