Enantioselective addition of diethylzinc to aldehydes catalysed by a β-amino disulfide derived fromL-proline
- 1 January 1996
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 5,p. 645-646
- https://doi.org/10.1039/cc9960000645
Abstract
A novel β-amino disulfide 2 is prepared and is effective at catalytic levels (1.25–2.5 mol%) in the enantioselective addition of diethylzinc to aldehydes providing (R)-secondary alcohols in up to 99% ee.Keywords
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