Gene Promoter Methylation in Plasma and Sputum Increases with Lung Cancer Risk
Open Access
- 15 September 2005
- journal article
- research article
- Published by American Association for Cancer Research (AACR) in Clinical Cancer Research
- Vol. 11 (18) , 6505-6511
- https://doi.org/10.1158/1078-0432.ccr-05-0625
Abstract
Purpose: Lung cancer is the leading cause of cancer mortality in the United States, due in part to the lack of a validated and effective screening approach for early detection. The prevalence for methylation of seven and three genes was examined in DNA from sputum and plasma, respectively, from women at different risk for lung cancer.Keywords
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