Neonatal pyridoxine responsive convulsions due to isoniazid therapy.
Open Access
- 1 July 1976
- journal article
- case report
- Published by BMJ in Archives of Disease in Childhood
- Vol. 51 (7) , 567-568
- https://doi.org/10.1136/adc.51.7.567
Abstract
A 17-day-old infant on isoniazid therapy 13 mg/kg daily from birth because of maternal tuberculosis was admitted after 4 days of clonic fits. No underlying infective or biochemical cause could be found. The fits ceased within 4 hours of administering intramuscular pyridoxine, suggesting an aetiology of pyridoxine deficiency secondary to isoniazid medication.Keywords
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