Neuron-glial relationship during regeneration of motorneurons
- 1 March 1989
- journal article
- review article
- Published by Springer Nature in Metabolic Brain Disease
- Vol. 4 (1) , 81-85
- https://doi.org/10.1007/bf00999498
Abstract
Following axonal interruption, structural, metabolic and physiological parameters change in motorneurons. Also, glial cells are involved in this process. Microglia proliferate and express new proteins such as vimentin or MHC antigens. Astrocytes show hypertrophy, increased GFAP synthesis, and formation of lamellae. Both glial cell types participate in deafferentation and insulation of regenerating neurons, a process with significance for post-lesioning functional impairment.Keywords
This publication has 30 references indexed in Scilit:
- Neuronal surface changes in the dorsal vagal motor nucleus of the guinea pig in response to axotomyJournal of Comparative Neurology, 1988
- The microglial cytoskeleton: vimentin is localized within activated cellsin situJournal of Neurocytology, 1988
- Delayed astrocyte reaction following facial nerve axotomyJournal of Neurocytology, 1988
- Production of superoxide anions by a CNS macrophage, the microgliaFEBS Letters, 1987
- Lectin binding by resting and reactive microgliaJournal of Neurocytology, 1987
- Ornithine decarboxylase in motoneurons during regenerationExperimental Neurology, 1985
- The glial reaction in the course of axon regeneration: A stereological study of the rat hypoglossal nucleusJournal of Comparative Neurology, 1984
- Changes in the composition of labeled protein transported in motor axons during their regenerationJournal of Neurobiology, 1980
- Neuroglial proliferation in the hypoglossal nucleus after nerve injuryExperimental Neurology, 1971
- Astroglial changes during retrograde atrophy of nucleus facialis in miceJournal of Comparative Neurology, 1955