Hereditary Thrombopathy Associated with Menorrhagia and Gastrointestinal Bleeding

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Abstract
Heredity thrombopathy is a qualitative platelet disorder characterized by abnormal platelet clotting function, but normal clot retraction and platelet clumping, Platelets are reduced in number and are of bizarre shapes and often enlarged. Three members of a family with this disease are reported and the complications of menorrhagia and gastrointestinal bleeding are discussed. Radiation castration has been effective in controlling menorrhagia, but gastrointestinal bleeding in men often resists all forms of therapy. The place of splenectomy in treatment of this disease is as yet undetermined.