Potentiating Effects of Materials of Plant and Animal Origin on Symptoms of Hypervitaminosis a in the Rat
- 1 August 1957
- journal article
- research article
- Published by Elsevier in Journal of Nutrition
- Vol. 62 (4) , 527-538
- https://doi.org/10.1093/jn/62.4.527
Abstract
Immature rats were fed a purified ration containing a massive but relatively non-toxic dose of vitamin A. Supplements of alfalfa meal and other succulent plants resulted in a significant potentiation of the symptoms of hypervitaminosis A. Both the dried alfalfa juice and the water-washed pulp remaining after the extraction of the juice were active in this regard. Desiccated liver, yeast, a product derived from fermentation sources8 and aureomycin HCl also showed activity. In contrast to the above, supplements of all the known nutrients had little if any potentiating effect.Keywords
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