Light-induced changes in the content of inositol phosphates in squid (Loligo pealei) retina
- 15 October 1987
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 247 (2) , 293-297
- https://doi.org/10.1042/bj2470293
Abstract
Illumination induced an increase in inositol polyphosphates, inositol 1,4-bisphosphate and inositol 1,4,5-trisphosphate, in the photoreceptors of the squid, Loligo pealei. There was a concomitant decrease in phosphatidylinositol 4,5-bisphosphate, but no light-induced change in any other phosphoinositide. None of these stimulus-induced changes were altered by treatment in vivo with pertussis toxin, which ADP-ribosylated a Mr-39000-peptide. These findings support the hypothesis that inositol 1,4,5-trisphosphate participates as either a messenger or a modulator in transduction in invertebrate photoreceptors.This publication has 26 references indexed in Scilit:
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