Inhibition of Muscle Cell Membrane ATPase by Quinidine.
- 1 February 1964
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 115 (2) , 324-325
- https://doi.org/10.3181/00379727-115-28902
Abstract
Summary The adenosinetriphosphatase activity of rat skeletal muscle membranes is inhibited about 45% by 5 × 10−4m quinidine sulfate and slightly (about 9%) by 5 × 10−5m quinidine sulfate. This enzymic activity requires sodium and magnesium. Higher concentrations of magnesium are inhibitory and the inhibitory effect of quinidine is decreased at high magnesium concentrations.Keywords
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