Serum Transaminases during Salicylate Therapy
- 22 May 1971
- Vol. 2 (5759) , 428-429
- https://doi.org/10.1136/bmj.2.5759.428
Abstract
In 8 out of 32 juvenile patients suffering from chronic polyarthritis and in one patient with dermatomyositis, raised transaminase levels were found; the salicylate level was above 35 mg/100 ml in all except one. Reduction in the salicylate level led to a prompt fall in the serum transaminases. Despite a rise in alkaline phosphatase in three cases there was no other evidence of liver dysfunction in the children. Only one of the adults showed a rise in transaminase levels, and she had mild cirrhosis.Keywords
This publication has 3 references indexed in Scilit:
- Hepatic involvement in juvenile rheumatoid arthritisThe Journal of Pediatrics, 1970
- Effect of Salicylate on the Activity of Plasma Enzymes in the RabbitNature, 1960
- Rapid determination of salicylate in biological fluidsBiochemical Journal, 1954