Class II HLA antigens in multiple sclerosis.
- 1 May 1989
- journal article
- research article
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 52 (5) , 575-577
- https://doi.org/10.1136/jnnp.52.5.575
Abstract
HLA typing in Wellington revealed a strong association of multiple sclerosis with DR2 than with DQw1. The association of DQw1 appeared to be due to linkage disequilibrium of this antigen with DR2. These results, when considered in conjunction with other studies, are most easily explained by the hypothesis that susceptibility to multiple sclerosis is influenced by multiple risk factors, with DR2 being an importnat risk factor in Caucasoid populations.Keywords
This publication has 28 references indexed in Scilit:
- A Population-Based Study of Multiple Sclerosis in TwinsNew England Journal of Medicine, 1986
- Ethnic and HLA patterns related to multiple sclerosis in Wellington, New Zealand.Journal of Neurology, Neurosurgery & Psychiatry, 1986
- HLA family studies and multiple sclerosis: A common gene, dominantly expressedHuman Immunology, 1981
- Immunoglobulin G heavy chain (Gm) allotypes in multiple sclerosis.Journal of Clinical Investigation, 1981
- Multiple sclerosis in the Orkney and Shetland Islands. III: Histocompatibility determinants.Journal of Epidemiology and Community Health, 1980
- DIFFERENT B LYMPHOCYTE ALLOANTIGENS ASSOCIATED WITH MULTIPLE SCLEROSIS IN ARABS AND NORTH EUROPEANSThe Lancet, 1977
- SEQUELÆ OF CONCUSSION CAUSED BY MINOR HEAD INJURIESThe Lancet, 1977
- HISTOCOMPATIBILITY DETERMINANTS IN MULTIPLE SCLEROSIS, WITH SPECIAL REFERENCE TO CLINICAL COURSEThe Lancet, 1973
- HL-A ANTIGENS AND MULTIPLE SCLEROSISPublished by Elsevier ,1972
- Multiple Sclerosis: Association with HL—A3Tissue Antigens, 1972