MONOCENTRIC MITOSIS WITH SEGREGATION OF CHROMOSOMES IN SCIARA AND ITS BEARING ON THE MECHANISM OF MITOSIS

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Abstract
This paper supplements earlier studies and considers findings in relation to the general problem of mitosis. Contrary to the generally accepted principles, an accurate segregation of chromosomes is effected in a unipolar field. Segregation is highly selective; paternal chromosomes react in opposite fashion from maternal homologs and pass away from the pole instead of toward it. Their behavior is believed to demonstrate functional reality of so-called "spindle fibers," which in this case retard move ment of the chromosomes. Also suggests that actual movement of chromosomes is due to an activity of chromosomes themselves (is autonomous), and is effected through localized alterations in viscosity of adjacent protoplasm. Experiments are reviewed which serve to show that retreating chromosomes are alive and functional during the mitosis.

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