Combination therapy targeting the tumor microenvironment is effective in a model of human ocular melanoma
Open Access
- 18 July 2007
- journal article
- Published by Springer Nature in Journal of Translational Medicine
- Vol. 5 (1) , 38
- https://doi.org/10.1186/1479-5876-5-38
Abstract
Ocular melanoma is the leading intraocular malignancy. There is no effective treatment for metastatic ocular melanoma. We sought a treatment targeting the tumor microenvironment as well as the tumor cells.Keywords
This publication has 20 references indexed in Scilit:
- Intra-arterial hepatic fotemustine for the treatment of liver metastases from uveal melanoma: experience in 101 patientsAnnals of Oncology, 2006
- Phase I Study of Hepatic Arterial Melphalan Infusion and Hepatic Venous Hemofiltration Using Percutaneously Placed Catheters in Patients With Unresectable Hepatic MalignanciesJournal of Clinical Oncology, 2005
- Uveal Melanoma: Epidemiologic AspectsOphthalmology Clinics of North America, 2005
- BAY 43-9006 Exhibits Broad Spectrum Oral Antitumor Activity and Targets the RAF/MEK/ERK Pathway and Receptor Tyrosine Kinases Involved in Tumor Progression and AngiogenesisCancer Research, 2004
- Application of Real-Time Cell Electronic Sensing (RT-CES) Technology to Cell-Based AssaysASSAY and Drug Development Technologies, 2004
- The evolution of thalidomide and its IMiD derivatives as anticancer agentsNature Reviews Cancer, 2004
- Role of Raf in Vascular Protection from Distinct Apoptotic StimuliScience, 2003
- Tumor Regression by Targeted Gene Delivery to the NeovasculatureScience, 2002
- Mutations of the BRAF gene in human cancerNature, 2002
- Endothelial apoptosis in Braf-deficient miceNature Genetics, 1997