Site-Directed Mutagenesis of Cytochrome P450eryF: Implications for Substrate Oxidation, Cooperativity, and Topology of the Active Site
- 24 May 2002
- journal article
- research article
- Published by American Chemical Society (ACS) in Chemical Research in Toxicology
- Vol. 15 (6) , 843-853
- https://doi.org/10.1021/tx025539k
Abstract
No abstract availableKeywords
This publication has 18 references indexed in Scilit:
- High-resolution crystal structure of cytochrome P450camPublished by Elsevier ,2005
- A Kinetic Model for the Metabolic Interaction of Two Substrates at the Active Site of Cytochrome P450 3A4Published by Elsevier ,2001
- Mammalian Microsomal Cytochrome P450 MonooxygenaseMolecular Cell, 2000
- Human cytochromes P450Molecular Aspects of Medicine, 1999
- Analysis of Four Residues within Substrate Recognition Site 4 of Human Cytochrome P450 3A4: Role in Steroid Hydroxylase Activity and α-Naphthoflavone StimulationArchives of Biochemistry and Biophysics, 1998
- Redox Control of the Catalytic Cycle of Flavocytochrome P-450 BM3Biochemistry, 1997
- Alanine-scanning Mutagenesis of a Putative Substrate Recognition Site in Human Cytochrome P450 3A4Journal of Biological Chemistry, 1997
- A Universal Approach to the Expression of Human and Rabbit Cytochrome P450s of the 2C Subfamily inEscherichia coliArchives of Biochemistry and Biophysics, 1995
- Crystal structure and refinement of cytochrome P450terp at 2·3 Å resolutionJournal of Molecular Biology, 1994
- Structure and absolute stereochemistry of the four N-phenylprotoporphyrin IX regioisomers isolated from phenylhydrazine-treated myoglobinJournal of the American Chemical Society, 1991