Effect of Dietary Sodium Restriction on Adrenal Cortical Response to ACTH.
- 1 March 1965
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 118 (3) , 792-795
- https://doi.org/10.3181/00379727-118-29972
Abstract
Summary In dogs fed a low sodium diet for 5 days before being hypophysectomized and nephrectomized, ACTH exerts a greater aldosterone-stimulating effect than it does in dogs fed approximately 40 mEq of sodium/day. Longer periods of sodium restriction produce a further increase in this action of ACTH. Seventeen-hydroxycorticoid output in response to various ACTH doses is unaffected.Keywords
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