Despite expression in embryonic visceral mesoderm, H2.0 is not essential for Drosophila visceral muscle morphogenesis
- 1 November 1991
- journal article
- research article
- Published by Wiley in Developmental Genetics
- Vol. 12 (3) , 206-211
- https://doi.org/10.1002/dvg.1020120305
Abstract
H2.0, a homeobox gene identified by homology to the Sex combs reduced homeobox of Drosophila, is expressed in all the cellular precursors of the visceral musculature. By analogy to the essential function of most other known homeobox genes in determining the fate of cells where they are expressed, we hypothesized that mutation of H2.0 would disrupt gut muscle development. In this paper, we show that a small deletion, which eliminates H2.0, has no detectable effect on normal gut morphogenesis, visceral muscle actin organization, or larval peristalsis.Keywords
This publication has 29 references indexed in Scilit:
- P-element-mediated enhancer detection: a versatile method to study development in Drosophila.Genes & Development, 1989
- The structure and function of the homeodomainBiochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1989
- The proboscipedia locus of the Antennapedia complex: a molecular and genetic analysis.Genes & Development, 1988
- mec-3, a homeobox-containing gene that specifies differentiation of the touch receptor neurons in C. elegansCell, 1988
- Pattern formation in the developing eye of Drosophila melanogaster is regulated by the homoeo-box gene, roughNature, 1988
- Organization of the cytoskeleton in early Drosophila embryos.The Journal of cell biology, 1986
- Isolation of a homoeo box-containing gene from the engrailed region of Drosophila and the spatial distribution of its transcriptsNature, 1985
- The engrailed locus of drosophila: Structural analysis of an embryonic transcriptCell, 1985
- A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexesNature, 1984
- Amatoxins, Phallotoxins, Phallolysin, and Antamanide: The Biologically Active Components of PoisonousAmanitaMushroomCRC Critical Reviews in Biochemistry, 1978